Cialis can be taken every 24 hours, but remember that the Cialis half-life is 36 hours. When mild vasodilators are taken in combination, blood-pressure-lowering effects of each individual compound may be increased. Individuals with “crowded” optic disc are also considered at greater risk for NAION compared to the general population; however, evidence is insufficient to support screening of prospective users of PDE5 inhibitors, including CIALIS, for this uncommon condition. Tell your doctor if tadalafil is not working well or if you are experiencing side effects. The penis is one of the areas where this enzyme works. Tadalafil is sometimes taken as needed, usually at least 30 minutes before sexual activity and not more often than once every 24 hours.Before you buy Cialis, check the cheap offer on Generic Pills for men and women from authorised, online pharmacy in the U.S., Canada, and worldwide. All year huge price discounts. Hurry up! For most individuals, the recommended starting dose of tadalafil is 10 mg per day taken before sexual activity (tadalafil for use as needed). Depending on the adequacy of the response or side effects, the dose may be increased to 20 mg or decreased to 5 mg a day. The effect of tadalafil may last up to 36 hours. Tadalafil (Cialis) is used to treat erectile dysfunction (ED, impotence; inability to get or keep an erection), and the symptoms of benign prostatic hyperplasia (BPH; an enlarged prostate) which include difficulty urinating (hesitation, dribbling, weak stream, and incomplete bladder emptying), painful urination, and urinary frequency and.