You’ll also need to fill out a medical questionnaire with answers about your medical history, current medications, and lifestyle habits. Cost-effective: Online platforms often offer competitive prices, discounts, and deals which can lead to significant savings. This is important for your overall health and safety, as certain medications can negatively interact with each other or cause existing conditions to worsen. Here are some key factors to consider when deciding: Pricing: Know how much your monthly supply will cost with shipping and tax. Some platforms have a digital pharmacy that ships the medication to your home, while others send an electronic prescription to your local pharmacy. What special precautions should I follow?Generic versions of Cialis that are FDA-approved are equally as effective and safe as brand-name Cialis. Generic versions are often less than half the cost. Last medically reviewed on November  · The typical dose for once-daily Cialis for ED is milligrams (mg) to 5 mg. When used as needed for ED, the usual Cialis dose is 10 mg (with a maximum daily dose of 20 mg). The typical dose of. How Cialis Works. Tadalafil and other PDE5 inhibitors primarily work by inducing muscle relaxation. Tadalafil stops the breakdown of a chemical responsible for relaxing muscles. In ED and PAH, the drug targets muscle cells in blood vessels. When the blood vessel muscle cells relax, this expands the vessel and increases blood flow; this .