Sit down until the feeling passes so that you do not fall and hurt yourself Headache Drink plenty of water and ask a pharmacist to recommend a suitable painkiller. Click here for an email preview. You can take it either with or without food. Store in a cool, dry place, away from direct heat and light. The goal of this meta-analysis was to provide more information about the efficacy and safety of dapoxetine in patients with PE.Dapoxetine is a selective serotonin reuptake inhibitor specifically designed to treat PE. This paper reviews the current evidence for use of dapoxetine in the treatment of PE in adult men.  · Purpose: Dapoxetine is the first oral agent approved for the treatment of premature ejaculation (PE). However, some countries have not approved its use. The goal of this meta-analysis was to provide more information about the efficacy and safety of dapoxetine in patients with PE. Dapoxetine, marketed as Priligy, among others, is a medication used for the treatment of premature ejaculation (PE) in men 18–64 years old. [3] [4] [5] Dapoxetine works by inhibiting the serotonin transporter, increasing serotonin’s action at the postsynaptic cleft, and as a consequence promoting ejaculatory delay. [6].