Neuropsychiatr Dis Treat ; No drug-drug interactions associated with dapoxetine have been reported If you have any problems with the way your liver works, or if you have any problems with the way your kidneys work. Perfect your technique. Also, they may be prescribed alone or with other treatments. Safety and efficacy of tramadol hydrochloride on treatment of premature ejaculation. Do you use recreational drugs?Premature ejaculation (PE) is a prevalent male sexual dysfunction. Current standard treatment regimens include behavioural therapies, topical anaesthetics, dapoxetine and . Dapoxetine, marketed as Priligy, among others, is a medication used for the treatment of premature ejaculation (PE) in men 18–64 years old. [3] [4] [5] Dapoxetine works by . Is there a pill for premature ejaculation? Yes, some pills can help premature ejaculation. Antidepressants and PDE5 inhibitors such as Viagra, can stop people from climaxing .